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Yes, heavy, long-term alcohol abuse can definitely cause severe brain damage leading to conditions like Alcohol-Related Dementia (ARD) (or Alcohol-Related Brain Damage, ARBD), which impairs memory, judgment, and thinking, and can also trigger psychological issues, including paranoia, as part of alcohol-induced psychosis or chronic mental health problems. Alcohol acts as a neurotoxin, destroying brain cells and affecting brain structure, potentially leading to cognitive decline, memory loss, and

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