Mar 20, 2017 · The objective of our research project was comparing culture methods ( batch, fed-batch, and perfusion processes ) using a bioprocess controller.

Abstract Animal cell culture technology has advanced significantly over the last few decades and is now generally considered a reliable, robust and relatively mature technology. A range of …

May 1, 2025 · A robust scale-down model development and process characterization for monoclonal antibody biomanufacturing using multivariate data analysis

Jul 12, 2024 · Monoclonal antibodies (mAbs) used in biomedical research and therapeutic applications are primarily produced by Chinese hamster ovary (CHO) cells via fed-batch …

Oct 7, 2024 · Cell culture plays a pivotal role in the development and production of biologics, from monoclonal antibodies to advanced cell therapies.

Jul 15, 2024 · Yes, as many of your listeners may know, antibody therapeutics typically achieve high titers and productivity in mammalian cell cultures. By implementing perfusion cell culture, …

Quality by Design principles are well described and widely used in biopharmaceutical industry. The characterization of a monoclonal antibody (mAb) production process is crucial for novel …

Feb 28, 2024 · Catechins prevent monoclonal antibody fragmentation during production via fed-batch culture of Chinese hamster ovary cells Tsuyoshi Yamaguchi, Hiroko Ishikawa, Mie Fukuda,

Monoclonal Antibody (mAb) Production The production of monoclonal antibodies (mAbs) follows a conventional biomanufacturing protocol, encompassing both cell culture and purification …

Process Development and Manufacturing Monoclonal antibodies (mAbs) are manufactured using a templated approach requiring robust, scalable, and regulatory compliant technologies to …