The San Francisco 49ers entered Saturday's game with just four running backs, and they lost one of them in the third quarter.

The San Francisco 49ers added some running back depth to their roster ahead of their preseason opener vs. the Denver Broncos.

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

Vaughn will solidify the 49ers' backfield depth with Isaac Guerendo (shoulder) and Jordan James (finger) both sidelined for a few weeks. Vaughn spent most of the 2024 season on the 49ers' practice ...

The 49ers are facing the Broncos in their first preseason game. Here are fiveplayers fans should keep their eyes on during ...

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled by halftime against the ...

The Radcliff, Ky. native was a wide receiver coming out of North Hardin. LOUISVILLE, Ky. - As fans of the Louisville football program know at this point, the Cardinals have an embarrassment of riches ...

The 49ers won't play their starters in their preseason debut against the Denver Broncos, but these 11 players will be worth ...

Nearly 40 players are brand new to the 49ers’ roster and poised to make their debut in Saturday’s preseason opener against ...

Fast forward to the present day, and running back is unequivocally Louisville's biggest strength heading into the upcoming ...

The key to winning any fantasy football league is identifying sleeper and breakout candidates and getting them on your roster ...

Browns rookie quarterback Shedeur Sanders completed 14-of-23 passes for 138 yards and two touchdowns, adding 19 rushing yards on four carries in the Browns preseason opener.