The EMBO Journal

Arginine methylation-dependent METTL14-SMN interaction regulates RNA m 6 A homeostasis

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. SMN interacts with METTL14 in an arginine ...
The EMBO Journal

Rewriting nuclear epigenetic scripts in mitochondrial diseases as a strategy for heteroplasmy control

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. High mtDNA mutation load triggers an ...
The EMBO Journal

Author Correction: Genotoxic stress triggers Scd6-dependent regulation of translation to modulate the DNA damage response

You are viewing the correction. This month's cover highlights the article Malaria parasites undergo a rapid and extensive metamorphosis after invasion of the host erythrocyte by Christiaan van Ooij, ...
The EMBO Journal

An AI-assisted morphoproteomic approach is a supportive tool in esophagitis-related precision medicine

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Esophagitis is a frequent, but at the ...
The EMBO Journal

The Dectin-1 and Dectin-2 clusters: C-type lectin receptors with fundamental roles in immunity

This month's cover highlights the article A novel bacterial effector protein mediates ER-LD membrane contacts to regulate host lipid droplets by Stacey D. Gilk, Rajendra Angara and Arif Sadi. The ...
The EMBO Journal

Palmitoylation by ZDHHC4 inhibits TRPV1-mediated nociception

Transient receptor potential vanilloid 1 (TRPV1) is a capsaicin-sensitive ion channel implicated in pain sensation. While TRPV1 potentiation in hyperalgesia development has been extensively ...
The EMBO Journal

Amplified centrosomes—more than just a threat

This month's cover highlights the article Nup358 restricts ER-mitochondria connectivity by modulating mTORC2/Akt/GSK3β signalling by Joseph, Misha Kalarikkal and colleagues. The image shows a human ...
The EMBO Journal

Astrocyte allocation during brain development is controlled by Tcf4-mediated fate restriction

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Astrocytes in the brain exhibit regional ...
The EMBO Journal

Molecular mechanism of β-arrestin-2 pre-activation by phosphatidylinositol 4,5-bisphosphate

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The mechanism of β-arrestin (βarr2) ...
The EMBO Journal

HIV-1 Vpu induces neurotoxicity by promoting Caspase 3-dependent cleavage of TDP-43

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Despite the efficacy of highly active ...
The EMBO Journal

Optimized PAR-2 RING dimerization mediates cooperative and selective membrane binding for robust cell polarity

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cell polarity networks are defined by ...