Individuals may have partial immunity, from previous infection or vaccination, to infection with influenza strains that have undergone antigenic drift. However, antigenic shift generates novel ...

Of more relevance to this year's experience is the phenomenon of antigenic drift. Drift is a subtler process than shift and involves the accumulation of mutations within the antibody-binding sites ...

Influenza and antigenic shift. Whereas antigenic drift affects all strains of influenza, antigenic shift only affects influenza A, as it has a broad range of animal reservoirs.

Antigenic shift causes an abrupt, major change resulting in new hemagglutinin and/or neuraminidase surface proteins. When antigenic shift happens, people often have little to no immunity.

Tamping down on Omicron may increase the risk of an ‘antigenic shift’ to a far deadlier supervariant.

Antigenic variation: Decoding the mechanism controlling antigen activation in trypanosomes. ScienceDaily . Retrieved June 11, 2025 from www.sciencedaily.com / releases / 2025 / 03 / 250313130806.htm ...

Antigenic Drift vs Antigenic Shift Even with careful research, a certain amount of educated guesswork is involved for manufacturers who select strains to incorporate into the annual flu vaccine.