Acquired factor V (FV) inhibitors are extremely rare and present with a broad spectrum ranging from asymptomatic laboratory anomalies to life-threatening critical bleeds. The overall rarity along with ...

Colonic melanoma is a rarely detected aetiology of small bowel obstruction. This is a case of a male in his 80s with a history of treated stage IIIA melanoma on his trunk 7 years prior who presented ...

Pseudoaneurysm is the formation of a sac due to damage in the continuity of the arterial wall. Iatrogenic carotid artery aneurysm is a rare, life-threatening complication following fine needle ...

Pulmonary hamartomas are abnormal growths of mature cell or tissue types, including cartilage, epithelium, fat or muscle. Although most cases are benign, asymptomatic and often incidentally discovered ...

A young man in his early 30s presented to our hospital with upper abdominal pain radiating to the back, progressive jaundice with pruritus, low-grade fever, vomiting and significant weight loss over 4 ...

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The solid variant of aneurysmal bone cyst is an expansile cystic lesion involving long tubular bones with unknown aetiology and usually occurs in the second decade of life. This is a paradigm of ...

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3 King's College London & Guy's and St. Thomas' PET Centre, London, UK A man in his 60s presented to the emergency department with central crushing chest pain on a background of a week’s history of ...

Cardiac tumours are often an incidental finding; when they do cause symptoms, they can be systemic (pyrexia and fatigue), cardiac (arrhythmia, chest pain and obstructive) or embolic (stroke, pulmonary ...

Acquired haemophagocytic lymphohistiocytosis (aHLH) is a rare and often fatal process of uncontrolled cytokine release driven by the inability of natural killer cells to eliminate infected or ...

Valproate (VPA) is broad-spectrum antiepileptic drug. Several adverse reactions including hepatotoxicity, fetal risk and pancreatitis are well known and labelled as boxed warnings in the USA. One ...