Davion Sykes' 17 points off of the bench helped lead Southern Illinois to an 83-54 victory against UT Martin on Wednesday.

Tired of the same old nature spots? Down in southern Illinois, this state park features unique sandstone formations and tons ...

Several Illinois sheriffs are calling for changes to the state’s Safe-T Act after Gov. J.B. Pritzker recently signaled he was ...

Damien Mayo Jr. scored 22 points to lead the Southern Illinois Salukis and Davion Sykes hit the game-winning layup with one second left as the Salukis took down the High Point Panthers 86-84 ...

Southern Illinois Healthcare (SIH) is opening the door to some of the most advanced cancer treatments in the world, ...

Southern Illinois takes on the UT Martin Skyhawks after Damien Mayo Jr. scored 22 points in Southern Illinois’ 86-84 win over the High Point Panthers ...

The Southern Seven Health Department, serving the southernmost counties of Southern Illinois encourages drivers to exercise ...

A 45-year-old woman who faces murder charges in connection to a judge's death in southern Illinois, now has a pre-trial ...

The ISA is now planning to partner with the Franklin County Sheriff’s Office in a pilot program that involves a partnership ...

YOUNGSTOWN, Ohio (AP) Beau Brungard accounted for six touchdowns, and Youngstown State scored on each of its five drives in the second half to beat Southern Illinois 48-38 on Saturday. Brungard ...

The shooting was reported at approximately 2:19 p.m. in Granite City, which is situated across the Mississippi River from St.

In Williamson County, Southern Illinois Healthcare is expanding access to advanced cancer clinical trials, including a global ...