Mahomes hit rookie wide receiver Xavier Worthy for a 54-yard touchdown, after Worthy just flat out-ran the cornerback and safety to the goal line. He secured the catch with only one hand — Chargers cornerback Kristian Fulton grabbed his other and was flagged for defensive pass interference. Didn’t matter.

Patrick Mahomes passed for 245 yards and a touchdown while rediscovering his connection with Travis Kelce, and the Kansas City Chiefs rallied from an early 10-point deficit to beat the Los Angeles Chargers 17-10.

The Kansas City Chiefs won their 10th straight game dating to last year on Sunday, as Patrick Mahomes led a comeback to defeat Justin Herbert and the Los Angeles Chargers 17-10. The Chargers jumped out to a 10-0 lead in the first quarter after the Chiefs turned the ball over on each of their first two possessions,

The Chiefs are the pick for each of 11 ESPN experts: Stephania Bell, Matt Bowen, Mike Clay, Dan Graziano, Jeremy Fowler, Kalyn Kahler, Kimberly Martin, Moses Moody, Jason Reid, Lindsey Thiry and Seth Wickersham.

Which teams will make a statement in their NFL Week 5 games? Check out our NFL Week 5 picks and NFL Week 5 predictions for the 14 NFL games this week. The Falcons won their game with a 58-yard field goal late against the Saints and face another NFC South opponent in this game.

The Kansas City Chiefs will look to keep their undefeated streak alive this week against the rival Los Angeles Chargers, in what is Patrick Mahomes' 100th career regular-season start. The Chiefs have won nine straight games including playoffs dating back to last year,