The 49ers are expected to be without starting quarterback Brock Purdy and tight end George Kittle, but they still have some weapons remaining on offense, and their defense is no picnic to deal with either.

Who's under pressure, and who is an X-factor? Why these players could be the difference in the New Orleans Saints' outcome against the 49ers:

The Seahawks sent Metcalf to Pittsburgh for the 52nd pick and a swap of late-round selections after the Steelers agreed to sign him to a four-year, $132 million extension that included $80 million in guarantees.

The New Orleans Saints are about to have a new leader in the clubhouse for games played in franchise history. Currently, that honor is held by longtime Saints

The New Orleans Saints ruled out three players on their final Week 2 injury report. Here's what you need to know before kickoff with the 49ers:

On Sunday New Orleans is debuts its "Gameday Gold" look against the Arizona Cardinals. It's the first time since 2002 that the Saints will wear gold on the field. The latest design is a modernized version of the original. New Orleans is also painting its end zones gold for the occasion.

Per Tankathon, the New Orleans Saints’ current draft position is the #1 pick.

A collection of the best offensive photos from the New Orleans Saints Week 5 game against the Seattle Seahawks on October 5, 2022. A collection of the best defensive photos from the New Orleans Saints Week 5 game against the Seattle Seahawks on October 9, 2022.

Opening a regular season with two road victories has been auspicious for the San Francisco 49ers under coach Kyle Shanahan.