In drug discovery trials, the potential for a molecule to do harm to an organism must be known accurately. Understanding how a substance under investigation behaves once in the body informs the design ...

Complete elimination of Human Immunodeficiency Virus (HIV) presents a challenge due to latent viral reservoirs within the body that can help re-establish infection. In a new paper, researchers propose ...

When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens if the dosage ...

BUFFALO, N.Y. — When you pop a prescription pill into your mouth, you trust it to address the issue it was meant to fix. But what really happens? How is your body processing the drugs and what happens ...

Antimicrobial pharmacodynamics attempts to link measures of drug exposure to the observed effect. This differs from other areas of pharmacodynamics because the main indicator of effect and the site of ...

Genetically engineered T-cell therapy for HPV-associated epithelial cancers: A first in human, phase I/II clinical trial. CD8 and PD-L1 determination in lung tumor tissue as prognostic biomarker and a ...

A phase 1, open-label, dose-escalation study of olaratumab as a single agent and in combination with doxorubicin, vincristine/irinotecan, or high-dose ifosfamide in ...

Explore our campus, meet lecturers and current students, and learn more about what it's like to study at Manchester. Qualify as a mathematical modeller with key skills in computational approaches in ...