When we think about iron imbalance, most people are familiar with iron deficiency and the health problems it can cause. What many may not realize is that the opposite problem, iron overload, can be ...

Iron overload is prevalent among adults with sickle cell disease (SCD), according to a study presented at the annual meeting of the American Society of Hematology, held from Dec. 6 to 9 in Orlando, ...

Study reveals liraglutide's potential to regulate iron metabolism and improve glucose tolerance in a mouse model of hereditary hemochromatosis and obesity. Study: Liraglutide Impacts Iron Homeostasis ...

Recently discovered genetic mutations, modern diagnostic techniques, and fresh approaches to therapy change the outlook on hemochromatosis. Ben, age 46, visited his primary-care clinician with ...

Prevalence is high (≈1:200–300 C282Y homozygotes; ≈1:8–10 carriers), but penetrance is incomplete, complicating broad screening policy and payer coverage decisions. Nonspecific presentations (fatigue, ...

BMP, bone morphogenetic protein; BMPR, bone morphogenetic protein receptor; HAMP, hepcidin; HFE, hereditary hemochromatosis protein; HJV, hemojuvelin; Holo-Tf, holo ...

For people who need blood transfusions, iron can accumulate in the heart and liver, causing damage and sometimes death. Doctors often prescribe medications called chelators that bind to iron and ...

Researchers at the University of Toronto and Toronto General Hospital have made a discovery that could prevent damage to the heart, pancreas and pituitary gland from excess iron with a simple pill.

Chronic iron accumulation renders neurons hypersensitive to oxidative stress, highlighting the importance of modeling ...

Sometimes, people with mild thalassemia may be told to supplement with iron. Iron supplements are only appropriate for certain types of thalassemia, though, and can be dangerous for people with more ...