Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, No. 4 (Feb. 15, 2000), pp. 1808-1812 (5 pages) From mutants of Escherichia coli unable to utilize fructose via ...
DNA-binding proteins survey genomes for targets using facilitated diffusion, which typically includes a one-dimensional (1D) scanning component for sampling local regions. Eukaryotic proteins must ...
DNA-binding proteins search for specific targets via facilitated diffusion along a crowded genome. However, little is known about how crowded DNA modulates facilitated diffusion and target recognition ...