Population genetics examines how harmful genetic variants arise, persist and are purged in natural and managed populations. Deleterious mutations reduce individual fitness and their fate is governed ...

Genome editing with CRISPR-Cas is often associated with the induction of mutations. However, a team of researchers from the Swiss University of Lausanne now shows that it can also be used to repair ...

The established conservation practice of relocating animals from large, genetically diverse populations to small communities of inbred endangered species may risk introducing more damaging than ...

Any detectable mitochondrial heteroplasmy was associated with increased incident CLL risk after multivariable adjustment in UK Biobank (HR 1.5), supporting mtDNA variation as a nontraditional risk ...

Mice pups conceived with in vitro fertilization (IVF) in the lab have slightly increased rates of DNA errors, or mutations, compared to pups conceived naturally, a new study on artificial reproductive ...

Picture of a tomato plant with an unfavorable natural mutation (on the left) and a tomato plant in with the mutation was repaired by genome editing (on the right). The repair of the mutation leads to ...