Although it also performs some functions in men, estrogen, the main female sex hormone, is involved in a myriad of processes, ...

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

Estrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of ...

Many genetic processes depend on proteins interacting with specific sequences on DNA. Despite the large excess of nonspecific DNA in the cell, proteins can locate their targets rapidly. After initial ...

Inside every human cell, six feet of DNA folds into a nucleus that is only a few micrometers wide, yet still manages to switch genes on and off with exquisite precision. The latest work on ...

Understanding the dynamic behavior of DNA remains an important challenge to biophysics, in particular the folding and stretching of DNA is critical since protein-DNA interactions require that the ...

Oestrogens, the main female sex hormone, although they also perform some functions in men, are involved in a myriad of processes, which is why the ...

Research chemists have a found a class of synthetic molecules that could quite literally act as a key which could lock away sections of DNA into a closely wound coil preventing proteins from ...

The double helix of DNA is one of the most iconic symbols in science. By imitating the structure of this complex genetic molecule we have found a way to make artificial muscle fibers far more powerful ...

Single-molecule real-time (SMRT) DNA sequencing 1 has opened many avenues in genomic interrogation 1,2,3. In SMRT sequencing, DNA strand replication by an individual DNA polymerase is optically ...