Predictions, picks and odds for NFL Week 10 game

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Week 10 NFL odds, lines, best bets, predictions: Computer model likes Buccaneers and 49ers
The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 10 on a sizzling 47-29 run on top-rated picks dating back to 2024. Anybody following its NFL betting picks at sportsbooks and on betting sites could have seen strong returns.

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Rams at 49ers: Predictions, picks and odds for NFL Week 10 game
How to watch San Francisco 49ers at New York Giants game for NFL Week 9
Bills vs. Dolphins best bets, picks and odds | Week 10 2025
The Buffalo Bills (6-2) face a fellow AFC East foe when they visit the Miami Dolphins (2-7) on Sunday, November 9, 2025 at Hard Rock Stadium, and if you're looking for best bets, we have them.

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Raiders vs Broncos: Predictions, picks, best bets for Week 10's Thursday Night Football matchup
Bills vs. Dolphins 2025 Week 10: Injured players, inactives, latest injury updates
Bills vs. Dolphins 2025 Prediction, Odds, Picks - Nov 9
In nine games, Tua Tagovailoa has 1,779 passing yards, with 15 touchdowns (10th in the NFL) against 11 interceptions and completing 67.9% of his attempts.

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Jordan Poyer, Buffalo Bills could surge vs. Dolphins in Week 10
Bears vs. Giants prediction, pick, odds for Sunday's NFL Week 10 game - 11/9/2025

Rams vs. 49ers: Three Key Matchups For Sunday's Key NFC West Bout

The Los Angeles Rams will do battle with NFC West division rival, the San Francisco 49ers in a game that could spark fireworks like it did last month on Thursda

Christian McCaffrey Makes NFL History in 49ers Game

The San Francisco 49ers got back to winning ways on Sunday, and it was thanks in large part to another strong performance from star running back Christian McCaffrey. The Niners were on the road at MetLife Stadium for Week 9. They took down the New York Giants, 34-24, to improve to 6-3 on the season.

Kyle Shanahan is keeping 49ers in playoff chase | NFL midseason awards

USA TODAY NFL columnist Jarrett Bell's midseason plaudits trumpet 49ers coach, Philly's QB, Browns' Myles Garrett.
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The 49ers need Trent Williams’ best game of 2025 against the Rams

2024 was a frustrating season for the 49ers and Williams. The season was lost for both the 49ers and Williams, as the left tackle played only 649 snaps. For reference, in 2025, Williams has played 612 snaps with eight fewer pass blocking snaps in 2025 than in 2024.
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