Week 10 College Football Betting Odds, Prediction
Digest more
Follow along as USC tries to keep its season alive by winning a road night game in the Big Ten, something it rarely does under Lincoln Riley:
What’s at stake, injuries, who’s better, key matchups, TV info and prediction for Saturday night’s Big Ten game in Lincoln.
Week 10 of the 2025 season is a pivotal point on the college football calendar. Not only does it mark the time at which almost every school in the nation will have played eight games -- or two-thirds of their schedule -- it also heralds the arrival of the first College Football Playoff rankings reveal.
No. 7 Ole Miss returns home Saturday to face South Carolina, as the Gamecocks seek to end a three-game skid against ranked foes.
That said, the Cornhuskers were one of the most-feared teams in college football history for multiple decades, a status given credence with the program's 930 all-time wins since debuting in 1890. The Cornhuskers have five claimed national championships, including two in 1970 and 1971.
The Purdue Boilermakers face the No. 21 Michigan Wolverines on Saturday, Nov. 1, 2025 at Michigan Stadium in Ann Arbor, Mich.
Lane Kiffin and the Ole Miss Rebels will host the South Carolina Gamecocks on Saturday night for a Week 10 SEC matchup at Vaught-Hemingway Stadium. After splitt
New users can get up to $2,000 in FanCash with the latest Fanatics Sportsbook promo code for Week 10 college football betting on Saturday