Lecce is a city in southern Italy and former capital of the province of Lecce, with the second-highest population in the Apulia region. It is on the S…Lecce is a city in southern Italy and former capital of the province of Lecce, with the second-highest population in the Apulia region. It is on the Salentine Peninsula, at the heel of the Italian Peninsula, and is over two thousand years old.