Grosse Pointe is a city in Wayne County in the U.S. state of Michigan. As of the 2020 census, the city had a population of 5,678. Grosse Point…Grosse Pointe is a city in Wayne County in the U.S. state of Michigan. As of the 2020 census, the city had a population of 5,678. Grosse Pointe is an eastern suburb of Metro Detroit along Lake St. Clair. It is located along East Jefferson Avenue and shares a small northwestern border with the city of Detroit. It is one of five cities within the Grosse Pointe area. Grosse Pointe was originally incorporated as a village in 1880 and then as a city in 1934.